Owner Nicole Graham works with volunteers from CFA and SES tries to dig out her horse “Astro” who became stuck up to his neck in mud at Avalon Beach on February 26, 2012 in Geelong, Australia. The tide was fast-rising, but the rescuers managed to get him out in time. (Photo by Peter Ristevski/Newspix)

Malian workers haul out a boat they use to carry sand collected from the river bed during a routine maintenance on October 7, 2018, in the port of Bamako. Increasing construction in the Malian capital has boosted the demand for bricks made out of high-quality Niger River sand. (Photo by Michele Cattani/AFP Photo)

A “Maya” girl sits in an altar during the traditional celebration of “Las Mayas” on the streets in Colmenar Viejo, near Madrid, Spain, Friday, May 2, 2014. The festivity of the Maya comes from pagan rites and dates from the medieval age, appearing in ancient documents, it takes place every year in the beginning of May and celebrates the beginning off the spring. A girl between 7 and 11years is chosen as “Maya” and should sit still, serious, and quiet for a couple of hours in an altar on the street decorated with flowers and plants, afterwards they walk to the church with their family where they attend a ceremony. (Photo by Daniel Ochoa de Olza/AP Photo)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

Behishta,11, listens during 4th grade class at the Zarghoona high school on July 25 2021 in Kabul, Afghanistan. The Zarghoona girls high school is the largest in Kabul with 8,500 female students attending classes. The school opened after a nearly two-month break due to the coronavirus (COVID-19) pandemic. (Photo by Paula Bronstein/Getty Images)

These Halloween horrors were all carved out of humble pumpkins by Ray Villafane and his team of professional sculptors who meticulously carved the terrifying characters using spoons and scalpels. Each one takes on average two hours to complete – with the horrifying results netting Villafane, plus colleagues Andy Bergholtz and Chris Vierra, numerous TV appearances each Halloween. This year the team has gone global travelling to Germany, Switzerland and Hong Kong to create their masterpieces. Photo: A horror face carved out of a pumpkin by Ray Villafane and team in Bellaire, Michigan. (Photo by Ray Villafane/Barcroft Media)

Shortlist, open competition, lifestyle. Healing Vibes – the hot springs of Bagno Vignoni in Italy flow out at a temperature of about 49°C. They were appreciated by the Romans for their healing powers, and have been used as therapeutic treatments since the 12th century, under Emperor Federico II. (Photo by Stefano Butturini/Sony World Photography Awards)

Granada’s International Poetry Festival is an extraordinary celebration of poetry that takes place across the entire city. For a week, every February, Granada is transformed into a virtual Capital of the World’s Poetry. Photo: A girl takes part in the “Burial of arrogance and haughtiness” carnival during the IX Poetry Festival in Granada, 45 km from Managua, Nicaragua on February 20, 2013. In this occasion the festival is dedicated to Nicaraguan poet Ernesto Cardenal. (Photo by Hector Retamal/AFP Photo)