In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

A group of young women have 'a bit of a do' for Oxfam at St Pancras International and enjoy a screening of the nation's favourite chick-flick Dirty Dancing on February 28, 2011 in London, England. Oxfam is calling on women across the UK to get together with their female friends in March to celebrate women's achievements for the 100th anniversary of International Women's Day (March 8, 2011) and raise money to support their work with women living in poverty. www.oxfam.org.uk/do (Photo by Ian Gavan/Getty Images for Oxfam). LONDON, ENGLAND – FEBRUARY 28

Space shuttle Atlantis (R) remains docked to the International Space Station photographed by NASA astronaut Ronald Garan during a planned six-and-a-half-hour spacewalk July 12, 2011 in space. Space shuttle Atlantis has embarked on a 12-day mission to the International Space Station where it will deliver the Raffaello multi-purpose logistics module packed with supplies and spare parts. This was the final mission of the space shuttle program, which began on April 12, 1981 with the launch of Colombia. (Photo by NASA via Getty Images)

James Castrission, “Cas” and Justin Jones “Jonesy” ski across an ice staking rink with two “You Can” patients on August 2, 2011 in Sydney, Australia. In 75 days, the Aussie adventure pair will attempt to cross 2,200 kilometres of Antarctic ice to the South Pole and back on foot to raise money for youth with cancer. The journey will require the two to trek with all the supplies for approximately three months of walking. Cas and Jonesy became the first to kayak unassisted over 3,300 kilometres from New Zealand to Australia in 2008. (Photo by Ryan Pierse/Getty Images)

Flowers are left at the scene of a hit and run following civil disturbances in the Winson Green area on August 11, 2011 in Birmingham, England. Police are continuing investigations after three people – reportedly trying to protect shops from rioting and looting in Dudley Road – were struck by a car. Police have so far arrested over 1,000 people following rioting which erupted over a four-day period across the UK. (Photo by Jeff J Mitchell/Getty Images)

A man takes a picture of part of what is set to be the UK's largest street art project on August 19, 2011 in Bristol, England. The See No Evil art project on Nelson Street in Bristol will see several multi story buildings in the street covered with art over the coming days. Organisers hope that the project, which has involved top graffiti artists from all over the world, will become a major tourist attraction for the west country city, often said to the spiritual home of Banksy. (Photo by Matt Cardy/Getty Images)

CANNES, FRANCE - NOVEMBER 03: Italian Prime Minister Silvio Berlusconi leaves the conference centre after the first day of the G20 Summit on November 3, 2011 in Cannes, France. World's top economic leaders are attending the G20 summit in Cannes on November 3rd and 4th, and are expected to debate current issues surrounding the global financial system in the hope of fending off a global recession and finding an answer to the Eurozone crisis. (Photo by Dan Kitwood/Getty Images)