“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

“Lombard Street is an east-west street in San Francisco, California. Lombard Street is best known for the one-way section on Russian Hill between Hyde and Leavenworth Streets, in which the roadway has eight sharp turns (or switchbacks) that have earned the street the distinction of being the crookedest street in the world”. – Wikipedia

Photo: A single car drives down a typically crowded Lombard Street, San Francisco's crooked street, April 29, 2003 in San Francisco. (Photo by Justin Sullivan/Getty Images)

The first load of passengers queuing for the Bennie Railplane in Glasgow; the inventor George Bennie is third in the queue. The streamlined cars are self propelled, driven by air screws in front and behind, and hang from a steel girder. (Photo by J. A. Hampton/Topical Press Agency/Getty Images). 4th July 1930

A veterinarian kisses an 8-month-old cat, wearing a prosthetic two-wheel device, at a veterinary hospital in Chongqing municipality, March 16, 2015. The cat's rear legs lost the abilty to walk after falling from the ninth to fifth floor of a building last November, its since undergone four major surgeries which included removing parts of its organs, local media reported. (Photo by Reuters/China Daily)

A teenager reacts as she receives a shot of the Sinovac vaccine for COVID-19 during a vaccination campaign at a school in Denpasar, Bali, Indonesia on Monday, July 5, 2021. (Photo by Firdia Lisnawati/AP Photo)

English television, radio presenter and DJ Maya Jama was alluring as Medusa at Maya Jama's annual Halloween party on October 30, 2021 in London, England. (Photo by mayajama/Instagram)

Sophie Turner (Sansa Stark) and George R. R. Martin attend the “Game Of Thrones” Season 8 NY Premiere on April 3, 2019 in New York City. (Photo by Jeff Kravitz/FilmMagic for HBO)

Japanese artist Sachi shows off her creation of a realistic 3D cat portrait, made by using felted wool, at her house in Sagamihara, Japan, January 21, 2022. (Photo by Akira Tomoshige/Reuters)