Wellcome trust employee Zoe Middleton poses behind an artwork entitled “My Soul” by Katharine Dowson, which consists of a laser etched lead chrystal glass formation in the shape of a brain, and was created using the artists own MRI Scan, at Wellcome Collection on March 27, 2012 in London, England. (Photo by Dan Kitwood/Getty Images)

Since its unveiling in 2006 this masterpiece created by Frank Gehry to house the Hotel Marqués de Riscal has become a highly sought after contemporary, luxury retreat. Design, art, gastronomy, wine and the lush landscape all combine to create a memorable sojourn.

A model presents a creation by Chinese designer Hu Sheguang from Sheguang Hu collection at China Fashion Week in Beijing, March 31, 2016. (Photo by Jason Lee/Reuters)

A model presents a creation during The Blonds Autumn/Winter 2017 collection during New York Fashion Week in the Manhattan borough of New York, U.S., February 14, 2017. (Photo by Brendan McDermid/Reuters)

A model presents a creation during the Cruise 2020 collection show for French fashion house Dior in Marrakech, Morocco, April 29, 2019. (Photo by Youssef Boudlal/Reuters)

Fan Bingbing attends the new High Jewellery Collection “Sortilege de Cartier” launch dinner at Villa Aurelia on September 17, 2011 in Rome, Italy. (Photo by Pascal Le Segretain/Getty Images for Cartier)

Aviation enthusiast Patrick Wilson 8, from Wetherby looks at an Avro 504 k at “The Shuttlesworth Collection” at Old Warden on July 21, 2014 in Biggleswade, England. Of the 55,000 planes that were manufactured by the Royal Army Corps (RAC) during WWI, only around 20 remain in airworthy condition. Six of these belong to The Shuttleworth Collection at Old Warden, Bedfordshire, making it the most complete collection of original airworthy WWI aircraft in the world. Amongst the collection is the SE5a. The SE5a is a single seater fighter aircraft. It is an original biplane designed by the Royal Aircraft Factory, with its engine built by Wolseley Motors Ltd, and it was issued to 84 Squadron in November 1918. The National Archive in Kew has recently verified that the plane saw action in France with 84 Squadron the day before Armistice, November 10, 1918. (Photo by Dan Kitwood/Getty Images)