Brain-on-a-chip. Dazzling in green and magenta this image shows the nerve fibres (in green) produced by neural stem cells (in magenta) as they grow on a synthetic gel. Captured by a technique known as confocal microscopy, the image is part of research shedding light on how tinkering with the environment can affect the way in which nerve fibres grow. (Photo by Collin Edington and Iris Lee/Massachusetts Institute of Technology/Wellcome Images)

A cadet lies on the grass after collapsing during a promotion ceremony at a police school in Bogota December 7, 2012. (Photo by John Vizcaino/Reuters)

In this Monday, March 18, 2019 photo, a street artist performs in Caracas, Venezuela. Venezuelans are facing a severe economic and political crisis as President Nicolas Maduro has remained in power despite heavy pressure from the United States and other countries arrayed against him, managing to retain the loyalty of most of Venezuela's military leaders. (Photo by Natacha Pisarenko/AP Photo)

A damaged vehicle is seen next to the ring road, around Skopje, near the village of Stajkovci, Skopje, The Former Yugoslav Republic of Macedonia, 08 August 2016. At least 21 people have died and more than 100 are injured in the heavy rain storm that hit the Macedonian capital Skopje late Saturday night causing severe damage to the roads and house infrastructure. More than 80 vehicles were hit by landslides at Skopje's ring road. The highway remains closed. The government announced a 15-day state of emergency in the Skopje and Tetovo region. (Photo by Georgi Licovski/EPA)

“Himalayan Dog”. This dog just appeared out of nowhere and followed us for an entire week during our trekking trip in the Himalayan outback. He always used to sleep in front of our tent and guarded us in the nights. When I decided to get up at 4 a.m. to climb the next 5000 m peak for sunrise he accompanied me as well. On the top he was sitting for the entire 30 minutes on this place looking straight into the countryside. Photo location: Ladakh, India. (Photo and caption by Sebastian Wahlhuetter/National Geographic Photo Contest)

Venezuela's food shortages, inflation and crumbling medical sector have become such a source of anguish that a growing number of young women are reluctantly opting for sterilizations rather than face the hardship of pregnancy and child-rearing. Traditional contraceptives like condoms or birth control pills have virtually vanished from store shelves, pushing women towards the hard-to-reverse surgery. While no recent national statistics on sterilizations are available, doctors and health workers say demand for the procedure is growing. (Photo by Carlos Garcia Rawlins/Reuters)

In a simpler time all a child or an adult needed to enjoy the outdoors was a ball and a stick. Or maybe an old tire tied to a high branch to fashion a swing. And the only instruction given to children was to “be home before dark”. Now there are iPads and computers and television screens and shrinking safe public spaces. But despite the distractions and limitations of space, these images show the charm of kicking a ball or skipping rope endures. Sometimes with modifications as a nod to changing times. Here: in this Saturday, June 20, 2015 photo, a boy runs while playing with a motorcycle wheel in Samugari, Ayacucho, Peru. (Photo by Rodrigo Abd/AP Photo)

The photography of Art Wolfe covers the globe, capturing landscapes, wildlife, and cultures from every continent; here he talks through a selection of his favourite images. Art Wolfe is an American photographer and conservationist. His photographs have been noted by environmental advocacy groups for their “stunning” visual impact. Here: Snowy owlets (Bubo scandiacus), Arctic National Wildlife Refuge, Alaska, USA. (Photo by Art Wolfe/Art Wolfe Stock)