Madeline is the first person with Down's syndrome to ever stride down a runway as a model during New York Fashion Week. Here: Model Madeline Stuart stands backstage between two male models at New York Fashion Week in New York City, U.S., September 6, 2018. (Photo by Andrew Kelly/Reuters)

A model is seen backstage before the Manish Arora Spring/Summer 2019 women's ready-to-wear collection show during Paris Fashion Week in Paris, France, September 27, 2018. (Photo by Stephane Mahe/Reuters)

Lottie Moss attends JULIEN MACDONALD presenting Julien X Gabriela Spring/Summer 2020 fashion show during London Fashion Week at Southwark Cathedral on September 16, 2019 in London, England. (Photo by David M. Benett/Getty Images for Julien Macdonald)

(L-R) Young Paris, Lionel Richie, Isabela Moner and Austin Butler attend the Jeremy Scott Fashion Show during New York Fashion Week at Spring Studios on September 8, 2017 in New York City. (Photo by Ben Gabbe/Getty Images)

Eleonora Brunacci and Mariano Di Vaio walk the red carpet ahead of the “Racer And The Jailbird (Le Fidele)” screening during the 74th Venice Film Festival at Sala Grande on September 8, 2017 in Venice, Italy. (Photo by Pascal Le Segretain/Getty Images)

In this picture taken Friday, September 8, 2017, Brazilan Samba dancers perform on stage during the Harare International Carnival in the capital. An international carnival aimed at boosting the local tourism industry has ended in economically troubled Zimbabwe. Some viewed the Harare festivities, which ended Sunday and featured artists and dancers from Brazil, Cuba, Egypt and elsewhere, as a relief from the struggle to get by in the southern African country. (Photo by Tsvangirayi Mukwazhi/AP Photo)

A car rolls south along the Dalton Highway near Coldfoot, Alaska, USA, 03 September 2017. Stretching 414 miles (666 kilometers) north from central Alaska to Prudhoe Bay, the Dalton Highway is one of America's northernmost roads and arguably its most remote. (Photo by Jim Lo Scalzo/EPA)

A couple have taken their love of animals to the extreme – by opening up their home to over 100 rescued animals. Dr Prakash Amte and his wife, Dr. Mandakini Amte have dedicated their lives to helping both the animals – and people – of Hemalkasa, Maharashtra in India. Here: Prakash Amte is seen playing with a Hyena from his orphanage on September 19, 2017 in Maharashtra, India. (Photo by Haziq Qadri/Barcroft Media)