Animal rights activists, including musician Kris Reichert, center, hold up signs with writing in Italian reading; “Leather: a lethal look” and “I wouldn't wear animal skin even if I were dead” as they stage a demonstration in front of Milan's Duomo gothic cathedral, Italy, Wednesday, September 20, 2017. Milan Fashion Week previews kick off Wednesday with Gucci, leading up to the awards on Sunday night. (Photo by Luca Bruno/AP Photo)