Beautiful, strange and occasionally alarming pictures from the shortlist for this year’s Wellcome image awards – which celebrate the very best in science photography and imaging – from an x-ray of a bat to a micrograph of a kidney stone. The exhibition opens on 12 March at three science centres and the Museum of Science and Industry in Manchester. Photo: Scanning electron micrograph (SEM) of an Arabidopsis thaliana flower, also commonly known as thale cress. Some of the anthers are open, revealing pollen grains ready for dispersal. Arabidopsis was the first plant to have its entire genome sequenced and is widely used as a model organism in molecular and plant biology. Horizontal width of image is 1200 microns. Magnification 100x. (Photo by Stefan Eberhard/Wellcome Images)

Hikaru Cho believes that we should challenge our imaginations to create new work using traditional tools, not fancy computers and software. (Photo by Jim Marks/PA Wire)

Brain-on-a-chip. Dazzling in green and magenta this image shows the nerve fibres (in green) produced by neural stem cells (in magenta) as they grow on a synthetic gel. Captured by a technique known as confocal microscopy, the image is part of research shedding light on how tinkering with the environment can affect the way in which nerve fibres grow. (Photo by Collin Edington and Iris Lee/Massachusetts Institute of Technology/Wellcome Images)

A three-seater Toyota Kikai concept car is displayed during the 2016 CES trade show in Las Vegas, Nevada January 8, 2016. (Photo by Steve Marcus/Reuters)

Shocking footage of a low-altitude flight through Brisbane's skyscrapers in United Kingdom on Thursday, September 23, 2021. The Royal Australian Air Force C-17 cargo jet was spotted on a practice run ahead of the annual Sunsuper Riverfire event, which took place on Saturday night. (Photo by The Mega Agency)

A participant of the Wild Sau Dirt Run 2015 passes a mud barrier in Obertriesting, Lower Austria, Austria, Saturday, April 4, 2015. The Wild Sau Dirt Run is a cross country and steeplechase race for men and women over the distances of 5, 10 and 20 kilometers (3.1, 6.2 and 12.4 miles). (Photo by Ronald Zak/AP Photo)

The extravagant residence Castello di Sammezzano sits on top of a hill in Tuscany, Northern Italy. Originally it was built in the Moorish style in 1605 for Ximenes d'Aragona and then re-designed between 1853 and 1889. After the war the castello was used as a luxury hotel until closure in the mid to late 1990's. It was abandoned until April 2012 when the FPXA committee was formed, aiming to promote and enhance the castle.