Cooler temperatures begin this week as a polar vortex brings much colder conditions with the chance of snow for Snowdonia, Ogwen Valley, North Wales on 22nd October 2018. The Ogwen Valley and Tryfan Mountain looking splendid in the Autumn sunrise. (Photo by DGDImages/Alamy Live News)

Alvine Uva, right, wrestles the winner's sash from the hands of newly-crowned Miss BumBum 2018 Ellen Santana, left after winning the Miss Bumbum Brazil 2018 pageant in Sao Paulo, Brazil on November 5, 2016. (Photo by Splash News and Pictures)

People watch as lava flows from an eruption of a volcano on the Reykjanes Peninsula in southwestern Iceland late on Monday, March 29, 2021. Iceland's latest volcano eruption is still attracting crowds of people hoping to get close to the gentle lava flows. The eruption in Geldingadalur, near Iceland's capital Reykjavik, is not seen as a threat to nearby towns and the slow flows mean people can get close to action without too much harm. (Photo by Marco Di Marco/AP Photo)

Belgian yoga teacher Dorien Dierckx, 29 from Brussels enjoys a beer while relaxing in a jacuzzi full of hot water and a mixture of ingredients used to make beer, and where customers can serve their own beer from the tap at the Good Beer Spa in Brussels, Belgium on May 12, 2021. (Photo by Yves Herman/Reuters)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

“Annelies Marie “Anne” Frank (12 June 1929 – early March 1945) was one of the most renowned and most discussed Jewish victims of the Holocaust. Acknowledged for the quality of her writing, her diary has become one of the world's most widely read books, and has been the basis for several plays and films”. – Wikipedia

Photo: Childrens watch the wax figure of Anne Frank and their hideout reconstruction at Madame Tussauds on March 9, 2012 in Berlin, Germany. (Photo by Andreas Rentz/Getty Images)

People take pictures of the sunset in Berlin October 27, 2014. (Photo by Hannibal Hanschke/Reuters)

The waning moon sets behind leafless sumac trees on a crisp, clear morning, Thursday, December 15, 2016, in Portland, Maine. Much of the northern Mid-Atlantic and Northeast will stay cold for the next couple of days as the arctic air remains stuck over the northern Appalachians, the National Weather Service said. (Photo by Robert F. Bukaty/AP Photo)