5-year-old Chinese girl Wang Anna prepares meals for her grandmother and great-grandmother at home in Zhuyuan village, Guizhou province, China on March 3, 2017. Chinese girl called Wang Anna, 5, takes care of her ill grandmother and 92-year-old great-grandmother on her own every day in a mountainous village in Zhima town, Zunyi city, southwest China's Guizhou province. Her father went to jail before she was born and her mother remarried after gave birth to her. Although she is just five years old, she started to shoulder the responsibility to look after ill grandmother and elderly great-grandmother. (Photo by Imaginechina/Rex Features/Shutterstock)

A “Maya” girl sits in an altar during the traditional celebration of “Las Mayas” on the streets in Colmenar Viejo, near Madrid, Spain, Friday, May 2, 2014. The festivity of the Maya comes from pagan rites and dates from the medieval age, appearing in ancient documents, it takes place every year in the beginning of May and celebrates the beginning off the spring. A girl between 7 and 11years is chosen as “Maya” and should sit still, serious, and quiet for a couple of hours in an altar on the street decorated with flowers and plants, afterwards they walk to the church with their family where they attend a ceremony. (Photo by Daniel Ochoa de Olza/AP Photo)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

Palestinian girl Manar Al-Shinbari (R), 15, who lost her both legs by what medics said was Israeli shelling at a UN-run school where she was taking refuge during the 50-day war last summer, is helped by her sister to put on her headscarf in an apartment in Jabaliya refugee camp in the northern Gaza Strip January 13, 2015. Manar's mother and three of her brothers were killed in the same incident. The girl's family house was destroyed by Israeli shelling during the war. (Photo by Mohammed Salem/Reuters)

Young girls take ballet lessons at the New Dreams dance studio in the Luz neighborhood known to locals as Cracolandia (Crackland) in Sao Paulo, Brazil, August 14, 2015. For the young girls learning to jump and plie, the dance studio provides a way forward and out of the difficult environment they have grown up in. Brazil is one of the world's highest consuming countries of crack cocaine, and Cracolandia, or “Crack Land”, located in the outskirts of Sao Paulo, is one of the most intense and brutal hubs. (Photo by Nacho Doce/Reuters)

This stirring collection of photos which offer a glimpse behind the scenes of army life have all been selected as winners in an annual competition. The remarkable pictures in the Army Photographic Competition show Britain's soldiers at work and play. They have been taken by amateur and professional soldier cameramen and include images from operations in Afghanistan, air shows and sporting events. The winners were announced at a ceremony held at the Army Headquarters in Andover in Hampshire. (Photo by Jamie Peters/MoD/Geoff Robinson Photography/REX Features)

Girls in Han costumes pose for a photo with blooming cherry blossoms at Yuyuantan Park during Qingming Festival holiday on April 4, 2022 in Beijing, China. Qingming Festival, also known as Tomb Sweeping Day, falls on April 5 this year. (Photo by Zhao Naiming/VCG via Getty Images)

A girl poses in antlers ahead of a curfew on pub in Nottingham, a city in central England’s Midlands region on September 21, 2020 as Freshers' Week got underway. Revellers were also pictured out in Birmingham, which was plunged into a local lockdown amid a surge in coronavirus cases. (Photo by Ashley Kirk/The Sun)