In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

This picture shows a two-year old orangutan seized from a residents house at the provincial Nature Conservation and Agency (BKSDSA) office in Banda Aceh on September 16, 2014. The critically-endangered primates population are dwindling rapidly due to poaching and rapid destruction of their forest habitat that is being converted into palm oil plantations. (Photo by Chaideer Mahyuddin/AFP Photo)

Students carry a female trainee who has fallen into a stupor during high intensity training at Tianjiao Special Guard/Security Consultant camp on the outskirts of Beijing December 1, 2013. Former Chinese soldier Chen Yongqing has big ambitions for his bodyguard training school Tianjiao, which he says is China's first professional academy to train former soldiers and others as personal security guards. Chen charges 500,000 yuan ($82,400) a year for each protector as China's rich and famous look to bolster their safety and sense of importance. (Photo by Jason Lee/Reuters)

The sun rises over the north sea as The Couple by artist Sean Henery sits just of the coast at Newbiggin-by-the-Sea, England, Wednesday October 8, 2014. (Photo by Owen Humphreys/AP Photo/PA Wire)

The carcass of a fattened pig, winner of the “holy pig” contest, is attached to a metal frame during a sacrificial ceremony in Sanxia district, in New Taipei City, Taiwan February 1, 2017. The winner of Taiwan's “holy pig” ceremony on Thursday defended the lunar new year tradition against critics who argue the fattened animals are raised under cruel conditions. (Photo by Tyrone Siu/Reuters)

Israeli soldiers of the Search and Rescue brigade take part in a training session in Ben Shemen forest, near the city of Modi'in May 23, 2016. (Photo by Amir Cohen/Reuters)

In this Saturday, Oct. 24, 2015 photo, a Lebanese Shiite supporter of Hezbollah with a tattoo on his head that reads in Arabic, “Oh Ali”, beats his chest during the holy day of Ashoura, in the southern suburb of Beirut, Lebanon. A growing number of Shiite Muslims in Lebanon are getting tattoos with religious and other Shiite symbols since the civil war in neighboring Syria broke out five years ago, fanning sectarian flames across the region. (Photo by Hassan Ammar/AP Photo)