In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

Actor George Clooney from the film “Ides Of March” arrives at the Hotel Excelsior during the 68th Venice Film Festival on August 31, 2011 in Venice, Italy. (Photo by Gareth Cattermole/Getty Images)

The new Citroen Concept Car Divine DS is presented at the 2014 Paris Auto Show on October 2, 2014 in Paris on the first of the two press days. European carmakers are hoping to impress with new models at this week's Paris Motor Show and prove they have come out stronger from years of economic trouble and cost-cutting. (Photo by Miguel Medina/AFP Photo)

The crowd watches as stunt pilots Melissa Pemberton, Jurgis Kairys and Skip Stewart of The Immortals fly past pyrotechnics as they perform at The Australian International Airshow on March 1, 2015 in Avalon, Australia. (Photo by Scott E. Barbour/Getty Images)

Shawn Layden, president and CEO of Sony Computer Entertainment America, addresses the audience during the Sony Playstation at E3 2015 news conference at the Los Angeles Sports Arena on Monday, June 15, 2015, in Los Angeles. (Photo by Chris Pizzello/Invision/AP)

A receptionist dinosaur robot performs at the new robot hotel, aptly called Henn na Hotel or Weird Hotel, in Sasebo, southwestern Japan, Wednesday, July 15, 2015. From the receptionist that does the check-in and check-out to the porter that’s a stand-on-wheels taking luggage up to the room, the hotel, that is run as part of Huis Ten Bosch amusement park, is “manned” almost totally by robots to save labor costs. (Photo by Shizuo Kambayashi/AP Photo)

A passenger aircraft passes over a residential house as it prepares to land at London Heathrow Airport in west London on October 17, 2016. Britain's government is considering whether to approve a third runway at Heathrow or expand air capacity in southeast England at another airport such as London Gatwick. (Photo by Daniel Leal-Olivas/AFP Photo)

Ireland's Philip Mulpeter, left, is kicked by Brazilian Vitor Nobrega during their welterweight mixed martial arts bout of International Pro Combat at the Estoril Casino in Estoril, near Lisbon, Portugal, Monday, January 26, 2015. Nobrega defeated Mulpeter. (Photo by Francisco Seco/AP Photo)