In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

Actor George Clooney from the film “Ides Of March” arrives at the Hotel Excelsior during the 68th Venice Film Festival on August 31, 2011 in Venice, Italy. (Photo by Gareth Cattermole/Getty Images)

Soldiers pose for a photo during the flower exhibition marking the 105th birth anniversary of the country's founding father, Kim Il Sung in Pyongyang, North Korea April 16, 2017. (Photo by Damir Sagolj/Reuters)

A woman smokes marijuana during the annual 4/20 marijuana rally on Parliament Hill in Ottawa, Ontario, Canada, April 20, 2017. (Photo by Chris Wattie/Reuters)

Juanita Robinson (L) from Ohio and Trenaya Blackburn pose as Quan White from Michigan takes their picture as they vacation on South Beach on May 16, 2016 in Miami Beach, Florida. The Florida government announced it broke a tourism record in the first quarter of this year, attracting 29.8 million tourists, an increase of 4.8 percent over the same time frame in 2015. (Photo by Joe Raedle/AFP Photo)

Caoimhe Cooburn-Gray poses for a picture on St. Patrick's day in Dublin, Ireland March 17, 2016. Saint Patrick's Day is a cultural and religious celebration held on 17 March, the traditional death date of Saint Patrick (c. AD 385–461), the foremost patron saint of Ireland. Celebrations generally involve public parades and festivals, céilithe, and the wearing of shamrocks, as well as green or orange attire. (Photo by Clodagh Kilcoyne/Reuters)

A model wears a floral head dress as she promotes a chain of garden centres at the Royal Horticultural Soceity's Chelsea Flower Show in London, Britain, May 18, 2015. (Photo by Toby Melville/Reuters)

A wax figure of U.S. actress Scarlett Johansson stands outside Madame Tussauds New York attraction shortly after the figure was unveiled in Times Square in New York, July 30, 2015. (Photo by Mike Segar/Reuters)