In this Tuesday, December 20, 2016 photo, Mohammad Ramzan, right, reacts while talking to The Associated Press with his young bride Saima in Jampur, Pakistan. Saima was given as a bride to the older man by her father so he could marry the groom’s sister, a practice of exchanging girls that is entrenched in conservative regions of Pakistan. It even has its own name in Urdu: Watta Satta, “give and take”. A mix of interests – family obligations, desire for sons, a wish to hand off a girl to a husband – can lead to a young teen in an a marriage she never sought. (Photo by K.M. Chaudhry/AP Photo)

A “Maya” girl sits in an altar during the traditional celebration of “Las Mayas” on the streets in Colmenar Viejo, near Madrid, Spain, Friday, May 2, 2014. The festivity of the Maya comes from pagan rites and dates from the medieval age, appearing in ancient documents, it takes place every year in the beginning of May and celebrates the beginning off the spring. A girl between 7 and 11years is chosen as “Maya” and should sit still, serious, and quiet for a couple of hours in an altar on the street decorated with flowers and plants, afterwards they walk to the church with their family where they attend a ceremony. (Photo by Daniel Ochoa de Olza/AP Photo)

Behishta,11, listens during 4th grade class at the Zarghoona high school on July 25 2021 in Kabul, Afghanistan. The Zarghoona girls high school is the largest in Kabul with 8,500 female students attending classes. The school opened after a nearly two-month break due to the coronavirus (COVID-19) pandemic. (Photo by Paula Bronstein/Getty Images)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

An Indian girl smiles under a water splash at a water park as the temperatures reached 38 degree Celsius in Calcutta, eastern India, 12 June 2016. The summer or pre-monsoon season lasts from March to July in eastern India with the highest day temperatures ranging from 38 to 45 degrees Celsius. (Photo by Piyal Adhikary/EPA)

A girl looks at other children practicing on a boxing ring during an exercise session at a boxing school, in the Mare favela of Rio de Janeiro, Brazil, June 2, 2016. For many young residents the Luta Pela Paz (Fight For Peace) academy offers a glimpse of an alternative: a chance to build discipline and self-esteem through boxing and martial arts. (Photo by Nacho Doce/Reuters)

A village girl, donning capes mostly of dried banana leaves and covered in mud, attends a mass in a bizarre annual ritual to venerate their patron saint, John the Baptist, Friday, June 24, 2016 at Bibiclat, Aliaga township, Nueva Ecija province in northern Philippines. (Photo by Bullit Marquez/AP Photo)

A girl attends Friday prayers in front of an army tank in Tahrir Square in Cairo February 18, 2011. Five years ago thousands of protesters took to the streets demanding the end of the 30-year reign of President Mubarak as Egypt became the second country to join the Arab Spring. After weeks of clashes, strikes and protests across Egypt, Mubarak resigned on February 11, 2011. (Photo by Suhaib Salem/Reuters)