A gallery assistant holds a rare 14th century time-telling device device in Bonhams auction house on December 9, 2011 in London, England. The instrument, which dates from 1396 and was discovered in a shed in Queensland, Australia, is due to be auctioned on December 13, 2011 and is expected to fetch 200,000 GBP. (Photo by Oli Scarff/Getty Images)

Charlotte Roirdan from Lyon & Turnbull views a letter written by Mary Queen of Scots on March 8, 2012 in Edinburgh, Scotland. The 450 year old letter, unearthed in Blair Castle in Ayrshire, has been verified as the hand writing of Mary Queen of Scotts and has been valued at 3,000 GBP. The letter, dated March 20, 1554, relieves the then laird of Blair from his duties due to gout and will be put up for sale next week at an auction in Edinburgh. (Photo by Jeff J. Mitchell/Getty Images)

Meatball, a bulldog, poses in a tuxedo at the Tompkins Square Halloween Dog Parade on October 20, 2012 in New York City. Hundreds of dog owners festooned their pets for the annual event, the largest of its kind in the United States. (Photo by John Moore)

Girls pose during a photocall to promote the Big Royal Wedding Sleepover at “Camp Royale” on Clapham Common on March 8, 2011 in London, England. The “Pop Up” campsite will cater for up to 10,500 people between April 28 and May 1 to coincide with the weekend of the Royal Wedding on April 29. (Photo by Dan Kitwood/Getty Images). LONDON, ENGLAND – MARCH 08 2011

A competitor tries to swipe away some grease as he slips off the “gostra”, a pole covered in grease, during the celebrations for the religious feast of St Julian, patron of the town of St Julian's, outside Valletta August 30, 2015. In the traditional “gostra”, a game stretching back to the Middle Ages, young men, women and children have to make their way to the top of a pole and try to uproot one of the flags to win prizes. Photo by Darrin Zammit Lupi/Reuters)

Beautiful, strange and occasionally alarming pictures from the shortlist for this year’s Wellcome image awards – which celebrate the very best in science photography and imaging – from an x-ray of a bat to a micrograph of a kidney stone. The exhibition opens on 12 March at three science centres and the Museum of Science and Industry in Manchester. Photo: Scanning electron micrograph (SEM) of an Arabidopsis thaliana flower, also commonly known as thale cress. Some of the anthers are open, revealing pollen grains ready for dispersal. Arabidopsis was the first plant to have its entire genome sequenced and is widely used as a model organism in molecular and plant biology. Horizontal width of image is 1200 microns. Magnification 100x. (Photo by Stefan Eberhard/Wellcome Images)

A Chinese future bride has her friends playing with her dress during a pre-wedding photoshoot in front of the Eiffel tower in Paris, France, August 28, 2015. As young Chinese become wealthier, they take abroad the tradition of taking their wedding photos days before they are married, rather than on their wedding day. (Photo by Philippe Wojazer/Reuters)