In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

Metropolitan Transit Authority (MTA) Police Officer Keith Flood trains with his K-9 partner Doc, a German Shepherd, inside the “warehouse room” at the new MTA Police Department Canine Training Center in Stormville, New York, U.S., June 6, 2016. (Photo by Mike Segar/Reuters)

In this Tuesday, July 14, 2015, photo, Phoe Thaw, center, a member of the White New Blood lethwei fighters club, a Myanmar traditional martial-arts club which practices a rough form of kickboxing, stretches during a practice session in their gym on a street in Oakalarpa, north of Yangon, Myanmar. Three of the club's members competed this summer on a stage a world away from the street gym: a mixed-martial-arts “One Championship” event broadcast globally on cable television networks, where fighters could receive $1,000 for each fight, according to coach Myint Zaw who started the traditional fighters' club 15 years ago. (Photo by Gemunu Amarasinghe/AP Photo)

A woman in traditional Malaysian attire welcomes leaders to the official dinner at the venue of the Association of Southeast Asian Nations (ASEAN) Summit in Kuala Lumpur, Malaysia November 21, 2015. (Photo by Jorge Silva/Reuters)

Members of the Dominican Armed Forces participate in a commemorative act on the 170th anniversary of national independence at the esplanade of Santo Domingo, on February 27, 2014. (Photo by Orlando Barria/EPA)

Find out what 2014 has in store for you and your cash. Provided by Russell Grant Horoscopes. (Photo by Toma Petrovic)

Vanessa, thirty-five, had three children with an abusive husband. She “lost her mind, started doing heroin”, after losing the children, who were taken away and given to her mother. The drugs led to homelessness and prostitution. She grew up on Arthur Avenue in the Bronx, but now spends her time in Hunts Point, “trying to survive everyday. Just doing whatever it takes”.

A visitor takes in a view of the downtown district from Twin Peaks on Friday, January 9, 2015, in San Francisco. (Photo by Marcio Jose Sanchez/AP Photo)