Back dropped by planet Earth the International Space Station (ISS) is seen from NASA space shuttle Endeavour after the station and shuttle began their post-undocking relative separation May 29, 2011 in space. After 20 years, 25 missions and more than 115 million miles in space, NASA space shuttle Endeavour is on the last leg of its final flight to the International Space Station before being retired and donated to the California Science Center in Los Angeles. Capt. Mark E. Kelly, U.S. Rep. Gabrielle Giffords' (D-AZ) husband, has lead mission STS-134 as it delivered the Express Logistics Carrier-3 (ELC-3) and the Alpha Magnetic Spectrometer (AMS-2) to the International Space Station. (Photo by NASA via Getty Images)