In this Friday, February 6, 2015 photo, sandhill cranes begin to stir after resting for the night at a roosting location along their winter migration route in Cecilia, Ky. According to counts made by biologists with the Kentucky Fish and Wildlife Resources, about 12,000 of the birds have stopped in Cecilia this week during their winter northward migration on their way to their nesting grounds in the Great Lakes region. (Photo by David Stephenson/AP Photo)

Members of the Knights Guard clean the ice during the Vegas Golden Knights' game against the Anaheim Ducks at T-Mobile Arena on January 14, 2021 in Las Vegas, Nevada. The Golden Knights defeated the Ducks 5-2. (Photo by Ethan Miller/Getty images/Profimedia)

New York City policemen tangled with demonstrators at a subway station on the opening day of the New York World's Fair, April 22, 1964. Youths attempted to stall the train, which was headed from the city to the fairgrounds, as a form of protest on behalf of civil rights for blacks. (Photo by Charles Gorry/AP Photo)

People clash with Venezuelan National Guards as they try to cross the border to Colombia over the Francisco de Paula Santander international bridge in Urena, Venezuela December 18, 2016. (Photo by Carlos Eduardo Ramirez/Reuters)

Nina Leen, one of the first female photographers to work for Life, took pictures for the magazine from 1940 to 1972. In the mid-1940s, her essay, “City Dogs”, featured actors and artists with their pets on the streets of New York City. In late-March, Daniel Cooney Fine Art in New York City, is opening a solo exhibition of Leen’s work that features images from that essay and others. Here: author Fannie Hurst clad in mink coat, enjoying the jumping antics of her Yorkshire terrier Orphan Annie on the street. (Photo by Nina Leen/Pix Inc./The LIFE Picture Collection/Getty Images)

Sad woman standing near car with scratch on parking and talking by the phone. (Photo by Vera Petrunina/Getty Images)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

“Lombard Street is an east-west street in San Francisco, California. Lombard Street is best known for the one-way section on Russian Hill between Hyde and Leavenworth Streets, in which the roadway has eight sharp turns (or switchbacks) that have earned the street the distinction of being the crookedest street in the world”. – Wikipedia

Photo: A single car drives down a typically crowded Lombard Street, San Francisco's crooked street, April 29, 2003 in San Francisco. (Photo by Justin Sullivan/Getty Images)