In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

This photo released by the Cleveland Animal Protective League shows Lurleen, the nursing mother and Noland the puppy snuggling up Wednesday, June 19, 2013, in Cleveland. Lurleen already is caring for four newborn kittens and now is nursing the orphaned week-old pit bull puppy in Cleveland. (Photo by AP Photo/Cleveland Animal Protective League)

A participant runs in high-heels as she competes in the Stiletto Run in Bucharest June 14, 2014. The annual 50 metres race requires participants to wear high-heels that are at least 7cm tall. (Photo by Bogdan Cristel/Reuters)

“Kilauea Rules”. The most extreme place we put ours kayakers to paddle till now. Photo location: Big Island, Hawaii. (Photo and caption by Alexandre Socci/National Geographic Photo Contest)

A large sand sculpture is seen at the site of Yokohama Sand Art Exhibition – Culture City of East Asia 2014 on July 16, 2014 in Yokohama, Japan. Producer and sand sculptor Katsuhiko Chaen invited artists from around the world including South Korea and China, to recreate the World Heritage and historical buildings in China, Japan and South Korea. The exhibition will be open from July 19 to November 3, 2014. (Photo by Chris McGrath/Getty Images)

Men push a motorbike through a street flooded by a river that overflowed from heavy rains caused by Hurricane Matthew in Leogane, Haiti, Wednesday, October 5, 2016. Rescue workers in Haiti struggled to reach cutoff towns and learn the full extent of the death and destruction caused by Hurricane Matthew as the storm began battering the Bahamas on Wednesday and triggered large-scale evacuations along the U.S. East Coast. (Photo by Dieu Nalio Chery/AP Photo)

Vendors selling marigold garlands, which are used to decorate temples and homes during the Hindu festival of Durga Puja, drink tea as they wait for customers at a wholesale flower market in Kolkata, India October 6, 2016. (Photo by Rupak De Chowdhuri/Reuters)

Comandos de Salvamento rescuers Maria Martinez (L) and Ana Chichilla attend to a wounded homeless man in San Salvador, El Salvador July 16, 2016. The man was attacked with a machete by suspected gang members. In 2015, El Salvador registered a record 103 homicides per 100,000 habitants, making it one of the most dangerous countries in the world outside a war zone. But for many young people who have few chances to distance themselves from rivalries between so-called maras in their schools and neighbourhoods, a civil-society organisation called the Comandos de Salvamento, or Rescue Corps, has been a refuge. (Photo by Jose Cabezas/Reuters)