In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

Roma's Gianluca Mancini scores his team's goal in the 1-0 Rome derby victory over Lazio at Stadio Olimpico in Rome, Italy on April 6, 2024. (Photo by Alberto Lingria/Reuters)

Napoli fans celebrate after winning the Coppa Italia final against Juventus FC, in central Naples, Italy on June 17, 2020. Napoli won the Italian Cup with a 4-2 penalty shootout victory over Juventus following a 0-0 draw in a match played at the Rome Olympic Stadium. (Photo by Salvatore Laporta/IPA/Rex Features/Shutterstock)

World War II enthusiasts take part in a re-enactament to mark the 70th anniversary of the Allied landings on Anzio beach, 52 km south of Rome, on January 25, 2014. (Photo by Andreas Solaro/AFP Photo)

A woman performs a dance during a demonstration for climate justice and against the war in Rome, Friday, March 25, 2022. Climate activists have staged a 10th series of worldwide protests to demand that leaders take stronger action against global warming. (Photo by Cecilia Fabiano/LaPresse via AP Photo)

“The Spanish Civil War (The Crusade among Nationalists, Fourth Carlist War among Carlists, The Rebellion or Uprising among Republicans) was a major conflict fought in Spain from 17 July 1936 to 1 April 1939. An estimated total of 500,000 people lost their lives as a consequence of the War”. – Wikipedia. Photo: Actors take part in a re-enactment of the “Battle of Areces” that took place during the Spanish Civil War, in Grullos, north of Spain, September 14, 2013. The re-enactment of the historic 1937 battle was organised by the Frente del Nalon Association. (Photo by Eloy Alonso/Reuters)