Wellcome trust employee Zoe Middleton poses behind an artwork entitled “My Soul” by Katharine Dowson, which consists of a laser etched lead chrystal glass formation in the shape of a brain, and was created using the artists own MRI Scan, at Wellcome Collection on March 27, 2012 in London, England. (Photo by Dan Kitwood/Getty Images)

Since its unveiling in 2006 this masterpiece created by Frank Gehry to house the Hotel Marqués de Riscal has become a highly sought after contemporary, luxury retreat. Design, art, gastronomy, wine and the lush landscape all combine to create a memorable sojourn.

A model presents a creation by Chinese designer Hu Sheguang from Sheguang Hu collection at China Fashion Week in Beijing, March 31, 2016. (Photo by Jason Lee/Reuters)

The President of the sushi restaurant chain Sushi Zanmai, Kiyoshi Kimura, cuts a blue fin tuna outside his main restaurant at the outer Tsukiji market in Tokyo January 5, 2015. The 180 kg blue fin tuna traded at a price of 4.5 million yen (37,500 USD) and was the most expensive fish at this year's New Year auction at the Tsukiji market, local media reported. (Photo by Thomas Peter/Reuters)

Elvish writing is seen on “Anduril”, a prop sword belonging to Aragorn, hero of “The Lord of the Rings” movie trilogy on July 31, 2014 in London, England. The sword, belonging to actor Sir Christopher Lee and estimated at $150,000-250,000, forms part of Bonhams “There's No Place Like Hollywood” movie memorabilia auction taking place in New York on November 24, 2014. (Photo by Peter Macdiarmid/Getty Images)

Two rare ceramic heads from a series by Japanese ceramicist Takahiro Kondo are displayed at the “Masterpiece London” Auction on June 29, 2011 in London, England. The second “Masterpieces London” sale is currently underway at The Royal Hospital Chelsea, showcasing fine and decorative arts, jewellery, classic cars, fine wines and sculpture from over 30 dealers. The event takes place from June 30 – July 5, 2011. (Photo by Dan Kitwood/Getty Images)

Aviation enthusiast Patrick Wilson 8, from Wetherby looks at an Avro 504 k at “The Shuttlesworth Collection” at Old Warden on July 21, 2014 in Biggleswade, England. Of the 55,000 planes that were manufactured by the Royal Army Corps (RAC) during WWI, only around 20 remain in airworthy condition. Six of these belong to The Shuttleworth Collection at Old Warden, Bedfordshire, making it the most complete collection of original airworthy WWI aircraft in the world. Amongst the collection is the SE5a. The SE5a is a single seater fighter aircraft. It is an original biplane designed by the Royal Aircraft Factory, with its engine built by Wolseley Motors Ltd, and it was issued to 84 Squadron in November 1918. The National Archive in Kew has recently verified that the plane saw action in France with 84 Squadron the day before Armistice, November 10, 1918. (Photo by Dan Kitwood/Getty Images)

Fan Bingbing attends the new High Jewellery Collection “Sortilege de Cartier” launch dinner at Villa Aurelia on September 17, 2011 in Rome, Italy. (Photo by Pascal Le Segretain/Getty Images for Cartier)