“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

People take pictures of the sunset in Berlin October 27, 2014. (Photo by Hannibal Hanschke/Reuters)

“Lombard Street is an east-west street in San Francisco, California. Lombard Street is best known for the one-way section on Russian Hill between Hyde and Leavenworth Streets, in which the roadway has eight sharp turns (or switchbacks) that have earned the street the distinction of being the crookedest street in the world”. – Wikipedia

Photo: A single car drives down a typically crowded Lombard Street, San Francisco's crooked street, April 29, 2003 in San Francisco. (Photo by Justin Sullivan/Getty Images)

“Annelies Marie “Anne” Frank (12 June 1929 – early March 1945) was one of the most renowned and most discussed Jewish victims of the Holocaust. Acknowledged for the quality of her writing, her diary has become one of the world's most widely read books, and has been the basis for several plays and films”. – Wikipedia

Photo: Childrens watch the wax figure of Anne Frank and their hideout reconstruction at Madame Tussauds on March 9, 2012 in Berlin, Germany. (Photo by Andreas Rentz/Getty Images)

Flames from the LNU Lightning Complex fires consume a home in unincorporated Napa County, Calif., on Wednesday, August 19, 2020. Fire crews across the region scrambled to contain dozens of wildfires sparked by lightning strikes. (Photo by Noah Berger/AP Photo)

Mei Hoshizuki and AZM compete during the Women's Pro-Wrestling “Stardom” at Korakuen Hall on September 28, 2020 in Tokyo, Japan. (Photo by Etsuo Hara/Getty Images)

WrestlerTeddy Sheedi (L) fights his opponent during the traditional Sindhi Malakhra wrestling in Karachi, Pakistan, 13 December 2020. A Malakhra match begins with both wrestlers tying a twisted cloth around the opponent's waist. Each one then holds onto the opponent's waistcloth and tries to throw him to the ground. (Photo by Shahzaib Akber/EPA/EFE)

A shopkeeper wears a face mask as a precaution against the coronavirus waits for customers at a market in Bengaluru, India, Friday, November 20, 2020. India's total number of coronavirus cases since the pandemic began has crossed 9 million. Nevertheless the country's new daily cases have seen a steady decline for weeks now and the total number of cases represents 0.6% of India's 1.3 billion population. (Photo by Aijaz Rahi/AP Photo)