In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

An authenticated contemporary copy of Leonardo da Vinci's Mona Lisa on display at the Prado Museum on February 1, 2012 in Madrid, Spain. Experts of the Prado Museum say the copy was painted at the same time as the Mona Lisa in Leonardo Da Vinci's studio by one of his students.

People try to board a goverment bus during the second day of a suspension of public transport services in Apopa, El Salvador July 28, 2015. Violent gangs in El Salvador ordered bus drivers to strike on Monday in a conflict that has killed six people and left thousands of commuters stranded on the streets of the Central American capital, police and bus company officials said. (Photo by Jose Cabezas/Reuters)

A sculptural artwork depicting former Chilean dictator Augusto Pinochet and headless presidents shot by a hooded high school student (not pictured) is seen at the Contemporary Art Museum in Santiago, December 2, 2014. The artwork, part of the “El ladrillo angular” (The angular brick) exhibition, portrays a student fighting against the ongoing continuity of dictatorship because of a political and economic system which has been impossible to destroy, according to “Papas Fritas” the artwork's creator. (Photo by Ivan Alvarado/Reuters)

The contest began in 2007, and since then photographers from more than 70 countries have entered. Photo: Michael O'Neal of San Francisco won first place in the animals category in the 2014 iPhone Photography Awards. (Photo by Michael O'Neal)

Nothing says Halloween like a jack-o'-lantern, but these professional carvings will blow your neighborhood pumpkin out of the water. (Photo by Frank C. Grace/Courtesy Jack-O-Lantern Spectacular)

Naki'o, a mixed-breed dog with four prosthetic devices, goes for a run in Colorado Springs April 12, 2013. Naki'o lost all four feet to frostbite when he was abandoned as a puppy in a foreclosed home. (Photo by Rick Wilking/Reuters)