In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

A girl poses at an entrance of her house next to a bomb dropped by the U.S. Air Force planes during the Vietnam War, in the village of Ban Napia in Xieng Khouang province, Laos September 3, 2016. From 1964 to 1973, U.S. warplanes dropped more than 270 million cluster munitions on Laos, one-third of which did not explode, according to the Lao National Regulatory Authority. (Photo by Jorge Silva/Reuters)

The sun rises over St Mary's Lighthouse in Whitley Bay on the Northumberland coast as a flock of Lapwing seabirds fly past on Wednesday, September 30, 2015. (Photo by Owen Humphreys/PA Wire)

The first seal pup to be born this season at a major colony of grey seals on the Farne Islands sits beside its mother on Brownsman Island, England on September 30, 2015. (Photo by Owen Humphreys/PA Images)

A Palestinian protester sets fire to himself as he throws a molotov cocktail during clashes with the members of the Israeli armed forces in the West Bank city of Hebron, 13 October 2015. The past 12 days have seen the worst spell of street violence in Israel and the Palestinian areas in years, stirred in part by Muslim anger over perceived changes to the status quo observed at a disputed Jerusalem holy site. Sixteen Palestinians from the West Bank and Jerusalem have been killed, but more than half of them have been attackers shot dead after or during attempts to stab Israelis. (Photo by Abed Al Hashlamoun/EPA)

In this Tuesday, December 15, 2015 photo, an Afghan man sells traditional sauces and pickles on a street in Kabul, Afghanistan. (Photo by Massoud Hossaini/AP Photo)

Children play in front of a brick factory on the outskirts of the northern Myanmar city of Mandalay on December 14, 2015. (Photo by Phyo Hein Kyaw/AFP Photo)

Fishermen move a fishing boat to a safer place along the shore ahead of cyclone Hudhud at Ganjam district in Odisha October 11, 2014. The India Meteorological Department described Cyclone Hudhud as a “very severe” storm that could pack winds of 195 kilometers (120 miles) per hour and cause torrential rains when it makes landfall near the port city of Visakhapatnam around noon Sunday. (Photo by Reuters/Stringer)