A mannequin with boots is stuffed upside down in the snow in front of a home in Nisswa, Minnesota, on March 18, 2013. (Photo by Steve Kohls/The Brainerd Daily Dispatch)

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Passengers prepare to take part in the No Pants Subway Ride in Prague, Czech Republic, Sunday, January 8, 2017. The No Pants Subway Ride began in 2002 in New York as a stunt and has taken place in cities around the world since then. (Photo by Petr David Josek/AP Photo)

A “Federahannes”, a jester figure from Rottweil, participates in the “Narrensprung” (jester jump) parade in Rottweil, southern Germany, Monday, February 27, 2016. About 4000 jesters paraded through the city among thousands of spectators. The Rottweil Narrensprung is the highlight of the Swabian-Alemannic Fastnacht and one of the traditional pre-Lenten carnival parades in southwestern Germany. (Photo by Michael Probst/AP Photo)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

A woman enjoys her last alcoholic drink on December 4, 2020 in Cardiff, Wales. Following a firebreak period that ran from October 23 to November 9 the Welsh Government have introduced new rules which will prevent pubs, restaurants and cafes from selling alcohol at any time from 6pm on Friday. The rules will be reviewed on December 17. (Photo by Wales News Service)

A teenager reacts as she receives a shot of the Sinovac vaccine for COVID-19 during a vaccination campaign at a school in Denpasar, Bali, Indonesia on Monday, July 5, 2021. (Photo by Firdia Lisnawati/AP Photo)

Palestinian groom Mohamed abu Daga and his bride Israa wear face masks amid the COVID-19 epidemic, during a photoshoot at a studio before their wedding ceremony in Khan Yunis in the southern Gaza Strip, on March 23, 2020. Authorities in Gaza confirmed on March 22 the first two cases of novel coronavirus, identifying them as Palestinians who had travelled to Pakistan and were being held in quarantine since their return, as the United Nations warned of potential disastrous outcomes to an outbreak given the high poverty rates and weak health system in the coastal strip, under Israeli blockade since 2007. (Photo by Said Khatib/AFP Photo)

Senator Barack Obama (D-IL) (R) stands in front of Senator Hillary Clinton (D-NY) as they arrive for U.S. President George W. Bush's annual State of the Union speech to a joint session of Congress at the U.S. Capitol in Washington in this January 23, 2007 file photo. Hillary Clinton announced her second run for the presidency on April 12, 2015 starting her campaign as the Democrats' best hope of fending off a crowded field of lesser-known Republican rivals and retaining the White House. (Photo by Larry Downing/Reuters)