In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

A chimpanzee looks in the direction of a camera at the Gut Aiderbichl Sanctuary for Traumatized Chimpanzees and other Primates in Gaenserndorf, near Vienna, 17 September 2018. 34 former laboratory chimpanzees of former Austrian pharmaceutical company Immuno AG spend their lives at the Gut Aiderbichl Sanctuary for Traumatized Chimpanzees and other Primates since 2009. (Photo by Christian Bruna/EPA/EFE)

Garbage pickers collect ride on donkey cart while looking for recyclable materials at a rubbish dump in the outskirts of Baghdad, Iraq, August 23, 2016. Despite its huge untapped oil and gas reserves and steadily rising oil output and revenue, 23 percent of the population live below the poverty line, according to the Ministry of Planning. (Photo by Khalid al Mousily/Reuters)

A young girl plays on the glass bottom platform of the Oriental Pear TV Tower as she travels with her family on the second day of the Chinese Lunar New Year holiday, also known as Spring Festival, in Shanghai, China on February 18, 2018. Some 287 million tourists travelled in China during the first four days of the week-long Chinese Lunar New Year holiday, up 11.1 percent from the same period last year, new data showed Sunday. (Photo by Imaginechina/Rex Features/Shutterstock)