In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

This photo released by the Cleveland Animal Protective League shows Lurleen, the nursing mother and Noland the puppy snuggling up Wednesday, June 19, 2013, in Cleveland. Lurleen already is caring for four newborn kittens and now is nursing the orphaned week-old pit bull puppy in Cleveland. (Photo by AP Photo/Cleveland Animal Protective League)

1st prize in the People Observed Portraits Stories category. Carla Kogelman, the Netherlands. The photo shows Hannah and Alena, two sisters living in the rural village of Merkenbrechts, Austria. (Photo by Carla Kogelman/World Press Photo)

In this Wednesday, May 23, 2012 photograph, a young deer and a cat share a moment in Feench village near Jodhpur, Rajasthan state, India. (Photo by AP Photo)

A chevrotain or mouse deer feeds in its enclosure at Zurich Zoo, Zurich, Switzerland, October 17, 2012. (Photo by Patrick B. Kraemer/AP)

Dominic Bergamin, left, a new Vatican Swiss Guard, is is kissed by his wife Joanne, prior to a swearing-in ceremony, at the Vatican, Wednesday, May 6, 2015. The ceremony is held each May 6 to commemorate the day in 1527 when 147 Swiss Guards died protecting Pope Clement VII during the Sack of Rome. (Photo by Ettore Ferrari/AP Photo/Pool Photo)

One of three young oriental small-clawed otters eats a meatball on June 18, 2015 in a zoo in Dresden, eastern Germany. The oriental small-clawed otter female Fussi gave birth to 3 healthy pups. Its pups now leave their burrow to explore the environment. (Photo by Arno Burgi/AFP Photo/DPA)

A landmark lion statue of a department store placed a protective mask is seen Wednesday, August 12, 2020, in Tokyo. The Japanese capital confirmed more than 200 new coronavirus cases on Wednesday. (Photo by Eugene Hoshiko/AP Photo)