“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

Behishta,11, listens during 4th grade class at the Zarghoona high school on July 25 2021 in Kabul, Afghanistan. The Zarghoona girls high school is the largest in Kabul with 8,500 female students attending classes. The school opened after a nearly two-month break due to the coronavirus (COVID-19) pandemic. (Photo by Paula Bronstein/Getty Images)

Young girls take ballet lessons at the New Dreams dance studio in the Luz neighborhood known to locals as Cracolandia (Crackland) in Sao Paulo, Brazil, August 14, 2015. For the young girls learning to jump and plie, the dance studio provides a way forward and out of the difficult environment they have grown up in. Brazil is one of the world's highest consuming countries of crack cocaine, and Cracolandia, or “Crack Land”, located in the outskirts of Sao Paulo, is one of the most intense and brutal hubs. (Photo by Nacho Doce/Reuters)

Palestinian girl Manar Al-Shinbari (R), 15, who lost her both legs by what medics said was Israeli shelling at a UN-run school where she was taking refuge during the 50-day war last summer, is helped by her sister to put on her headscarf in an apartment in Jabaliya refugee camp in the northern Gaza Strip January 13, 2015. Manar's mother and three of her brothers were killed in the same incident. The girl's family house was destroyed by Israeli shelling during the war. (Photo by Mohammed Salem/Reuters)

As part of FLAIR Melbourne – a Flinders Lane art festival – Melbourne’s Lisa Minogue presents stylised photographic portraits of Australian women of colour, their faces painted vibrantly to accentuate their individuality and encourage the viewer to study each face more closely. Minogue asked each woman the same question: “What do the words “coloured girl” mean to you?”. (Photo by Lisa Minogue/The Guardian)

5-year-old Chinese girl Wang Anna prepares meals for her grandmother and great-grandmother at home in Zhuyuan village, Guizhou province, China on March 3, 2017. Chinese girl called Wang Anna, 5, takes care of her ill grandmother and 92-year-old great-grandmother on her own every day in a mountainous village in Zhima town, Zunyi city, southwest China's Guizhou province. Her father went to jail before she was born and her mother remarried after gave birth to her. Although she is just five years old, she started to shoulder the responsibility to look after ill grandmother and elderly great-grandmother. (Photo by Imaginechina/Rex Features/Shutterstock)

As the world marks the International Day of the Girl Child, women's rights activists point to progress on a wide array of issues but say more needs to be done to protect girls from child marriage, sexual assault and other forms of exploitation. Here is a selection of pictures showing the daily lives of girls across the globe, all taken by female Associated Press photojournalists. Here: In this December 14, 2015, file photo, a young clown rides in the back of a car following a procession to the Basilica of Our Lady of Guadalupe in Mexico City. Hundreds belonging to various clown associations made their annual pilgrimage to the Basilica to pay their respects to the Virgin of Guadalupe, Mexico's patron saint. (Photo by Rebecca Blackwell/AP Photo)

In this September 10, 2016 picture, a girl takes pictures of a fellow contestant while warming up backstage before competing in the Romania Miss Pole Dance Contest, ahead of the finals of the Pole Sport&Fitness World Championship 2016 in Bucharest, Romania. (Photo by Vadim Ghirda/AP Photo)