In this Tuesday, December 20, 2016 photo, Mohammad Ramzan, right, reacts while talking to The Associated Press with his young bride Saima in Jampur, Pakistan. Saima was given as a bride to the older man by her father so he could marry the groom’s sister, a practice of exchanging girls that is entrenched in conservative regions of Pakistan. It even has its own name in Urdu: Watta Satta, “give and take”. A mix of interests – family obligations, desire for sons, a wish to hand off a girl to a husband – can lead to a young teen in an a marriage she never sought. (Photo by K.M. Chaudhry/AP Photo)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

A “Maya” girl sits in an altar during the traditional celebration of “Las Mayas” on the streets in Colmenar Viejo, near Madrid, Spain, Friday, May 2, 2014. The festivity of the Maya comes from pagan rites and dates from the medieval age, appearing in ancient documents, it takes place every year in the beginning of May and celebrates the beginning off the spring. A girl between 7 and 11years is chosen as “Maya” and should sit still, serious, and quiet for a couple of hours in an altar on the street decorated with flowers and plants, afterwards they walk to the church with their family where they attend a ceremony. (Photo by Daniel Ochoa de Olza/AP Photo)

Behishta,11, listens during 4th grade class at the Zarghoona high school on July 25 2021 in Kabul, Afghanistan. The Zarghoona girls high school is the largest in Kabul with 8,500 female students attending classes. The school opened after a nearly two-month break due to the coronavirus (COVID-19) pandemic. (Photo by Paula Bronstein/Getty Images)

Granada’s International Poetry Festival is an extraordinary celebration of poetry that takes place across the entire city. For a week, every February, Granada is transformed into a virtual Capital of the World’s Poetry. Photo: A girl takes part in the “Burial of arrogance and haughtiness” carnival during the IX Poetry Festival in Granada, 45 km from Managua, Nicaragua on February 20, 2013. In this occasion the festival is dedicated to Nicaraguan poet Ernesto Cardenal. (Photo by Hector Retamal/AFP Photo)

A Syrian refugee girl covers herself with a blanket as she stands outside tents at a makeshift settlement in Bar Elias in the Bekaa valley January 5, 2015. Lebanon enforced new immigration controls at the Syrian border on Monday in a move to gain control of the steady stream of refugees from its much larger neighbour. (Photo by Mohamed Azakir/Reuters)

In this undated handout photograph from the “Inside Out Project”, a poster bearing the image of a Pakistani girl whose parents, lawyers say, were killed in a drone strike, lies in a field at an undisclosed location in the northwestern Khyber-Pakhtunkhwa province. A group of artists in Pakistan are hoping to generate “empathy” among US drone operators by placing giant posters of children in the country's troubled tribal regions. (Photo by AFP Photo)

A security personnel plays with a girl in the compound of a health and rest centre which serves as a temporary accommodation for refugees from eastern regions of the country in the town of Korostyshiv, Zhytomyr region, Ukraine, July 30, 2015. More than 400 people who left eastern Ukraine due to a military conflict have arrived at the sanatorium in Korostyshiv since the summer of 2014, according to representatives. (Photo by Valentyn Ogirenko/Reuters)