In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

A girl collects drinking water at Dala river outside Yangon, Myanmar March 3, 2016. Some 650 million people, or one in 10 of the world's population, have no access to safe water, putting them at risk of infectious diseases and premature death. Dirty water and poor sanitation can cause severe diarrhoeal diseases in children, killing 900 under-five a day across the world, according to United Nations estimates. (Photo by Soe Zeya Tun/Reuters)

Carlos Melendez prepares to feed his pet squirrel “Colita” in downtown San Salvador January 29, 2015. (Photo by Jose Cabezas/Reuters)

A relative (L) of Champa Devi, 88, sits next to her body, minutes after her death at Mukti Bhavan (Salvation House) at Varanasi, in the northern Indian state of Uttar Pradesh, June 21, 2014. The city of Varanasi, on the banks of the River Ganges, is widely considered Hinduism's holiest city and many Hindus believe that dying there and having their remains scattered in the Ganges allows their soul to escape a cycle of death and rebirth, attaining “moksha” or salvation. “Mukti Bhavan” or “Salvation House”, is a charity-run hostel that caters for people who wish to come to Varanasi to die. Guests can normally stay up to two weeks after which, if they haven't yet passed away, they are gently asked to leave. (Photo by Danish Siddiqui/Reuters)

An empty cell block is pictured within Joint Task Force Guantanamo's Camp VI at the U.S. Naval Base in Guantanamo Bay, Cuba March 22, 2016. (Photo by Lucas Jackson/Reuters)

“The Net thrower”. The fisherman are conducting activities on Situgunung Lake. Photo location: Situgunung lake, Sukabumi, West Java, Indonesia. (Photo and caption by Dody Kusuma/National Geographic Photo Contest)

Girls take a selfie at the haze shrouded Batanghari River bridge in Jambi, Indonesia Sumatra island, September 14, 2015. Indonesian islands are blanketed in the so-called “haze”, caused by slash-and-burn clearances on the islands of Sumatra and Borneo, which makes thousands sick, delays flights and pushes air quality to unhealthy levels in neighboring Singapore and Malaysia. (Photo by Reuters/Beawiharta)

A miner with a donkey makes his way through the low and narrow tunnel leading out of a coal mine in Choa Saidan Shah in Punjab province, April 29, 2014. Workers at this mine in Choa Saidan Shah dig coal with pick axes, break it up and load it onto donkeys to be transported to the surface. Employed by private contractors, a team of four workers can dig about a ton of coal a day, for which they earn around $10 to be split between them. The coalmine is in the heart of Punjab, Pakistan's most populous and richest province, but the labourers mostly come from the poorer neighbouring region of Khyber Pakhtunkhwa. (Photo by Sara Farid/Reuters)