In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

Actor George Clooney from the film “Ides Of March” arrives at the Hotel Excelsior during the 68th Venice Film Festival on August 31, 2011 in Venice, Italy. (Photo by Gareth Cattermole/Getty Images)

A three-seater Toyota Kikai concept car is displayed during the 2016 CES trade show in Las Vegas, Nevada January 8, 2016. (Photo by Steve Marcus/Reuters)

The Berenson robot strolls among visitors during the exhibition “Persona : Oddly Human” at the Quai Branly museum in Paris, France, February 23, 2016. The Berenson robot, developed in France in 2011, is the brainchild of anthropologist Denis Vidal and robotics engineer Philippe Gaussier. Its programming allows it to record reactions of museum visitors to certain pieces of art and then use the data to develop its own unique taste, which allows “Berenson” to judge whether or not it likes a certain work of art within an exhibition. (Photo by Philippe Wojazer/Reuters)

A young Indian girl dressed as Hindu goddess Laxmi participates in a procession to mark “Gudi Padwa”, or Maharashtrian New Year, in Mumbai, in the Indian state of Maharashtra, Friday, April 8, 2016. (Photo by Rajanish Kakade/AP Photo)

A student activist is detained during a silent protest after Thailand's election commission filed charges against a group for posting “foul and strong” comments online criticising a military-backed draft constitution, in Bangkok, Thailand April 27, 2016. (Photo by Jorge Silva/Reuters)

Chinese tourists watch storm clouds moving along the coast towards the city of Sydney, Australia, November 6, 2015. Powerful storms swept across the city on Friday, with the Australian Bureau of Meteorology issuing a warning for severe thunderstorms with large hailstones, heavy rainfall and damaging winds, local media reported. (Photo by David Gray/Reuters)

The crowd watches as stunt pilots Melissa Pemberton, Jurgis Kairys and Skip Stewart of The Immortals fly past pyrotechnics as they perform at The Australian International Airshow on March 1, 2015 in Avalon, Australia. (Photo by Scott E. Barbour/Getty Images)