In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

A fellow officer comes to the aid of injured patrolman C.V. Satt, who was pelted with rocks and beer bottles during a clash between police and relief demonstrators in Denver September 23, 1935. (Photo by Henry G. Eisenhand/AP Photo)

A man walks his dog as the sun sets in a park in Frankfurt, Germany, Monday, September 18, 2017. Cool damp weather is set to continue in this part of Germany for the next few days with temperatures in the mid teens Celsius. (Photo by Michael Probst/AP Photo)

Filipino villagers escape to a safe area as the Mayon Volcano erupts anew in the town of Daraga, Albay province, Philippines, 23 January 2018. The Philippine Institute of Volcanology and Seismology (PHIVOLCS) agency on 22 January raised the alert level for the Mayon Volcano amid fears of a bigger eruption over the next few hours or days. (Photo by Francis R. Malasig/EPA/EFE)

English fashion designer Mary Quant (R) with a group of models at Heathrow Airport, before leaving for a continental fashion tour, 18th March 1968. (Photo by Express/Getty Images)

In this Tuesday, March 20, 2018 photo, a Vampire Bat drinks bovine blood in the Criaturas de la Noche (Creatures of the Night) Bat House, the Audubon Zoo's new night house in New Orleans. The various species are all from Central and South America, and the building's interior simulates an abandoned warehouse set up to protect Mayan artifacts during a dig. (Photo by Gerald Herbert/AP Photo)

One of three young oriental small-clawed otters eats a meatball on June 18, 2015 in a zoo in Dresden, eastern Germany. The oriental small-clawed otter female Fussi gave birth to 3 healthy pups. Its pups now leave their burrow to explore the environment. (Photo by Arno Burgi/AFP Photo/DPA)

Job seekers carry a woman who fainted at the Indonesia Spectacular Job Fair 2015 at Gelora Bung Karno stadium in Jakarta August 12, 2015. Indonesia's gross domestic product grew at 4.67 percent in the second quarter, its slowest pace in six years. Since he took office last October, Widodo's government has passed a raft of measures aimed at boosting industry and consumption that have been criticized by investors as protectionist. (Photo by Reuters/Beawiharta)