“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

A “Maya” girl sits in an altar during the traditional celebration of “Las Mayas” on the streets in Colmenar Viejo, near Madrid, Spain, Friday, May 2, 2014. The festivity of the Maya comes from pagan rites and dates from the medieval age, appearing in ancient documents, it takes place every year in the beginning of May and celebrates the beginning off the spring. A girl between 7 and 11years is chosen as “Maya” and should sit still, serious, and quiet for a couple of hours in an altar on the street decorated with flowers and plants, afterwards they walk to the church with their family where they attend a ceremony. (Photo by Daniel Ochoa de Olza/AP Photo)

Behishta,11, listens during 4th grade class at the Zarghoona high school on July 25 2021 in Kabul, Afghanistan. The Zarghoona girls high school is the largest in Kabul with 8,500 female students attending classes. The school opened after a nearly two-month break due to the coronavirus (COVID-19) pandemic. (Photo by Paula Bronstein/Getty Images)

As part of FLAIR Melbourne – a Flinders Lane art festival – Melbourne’s Lisa Minogue presents stylised photographic portraits of Australian women of colour, their faces painted vibrantly to accentuate their individuality and encourage the viewer to study each face more closely. Minogue asked each woman the same question: “What do the words “coloured girl” mean to you?”. (Photo by Lisa Minogue/The Guardian)

5-year-old Chinese girl Wang Anna prepares meals for her grandmother and great-grandmother at home in Zhuyuan village, Guizhou province, China on March 3, 2017. Chinese girl called Wang Anna, 5, takes care of her ill grandmother and 92-year-old great-grandmother on her own every day in a mountainous village in Zhima town, Zunyi city, southwest China's Guizhou province. Her father went to jail before she was born and her mother remarried after gave birth to her. Although she is just five years old, she started to shoulder the responsibility to look after ill grandmother and elderly great-grandmother. (Photo by Imaginechina/Rex Features/Shutterstock)

As the world marks the International Day of the Girl Child, women's rights activists point to progress on a wide array of issues but say more needs to be done to protect girls from child marriage, sexual assault and other forms of exploitation. Here is a selection of pictures showing the daily lives of girls across the globe, all taken by female Associated Press photojournalists. Here: In this December 14, 2015, file photo, a young clown rides in the back of a car following a procession to the Basilica of Our Lady of Guadalupe in Mexico City. Hundreds belonging to various clown associations made their annual pilgrimage to the Basilica to pay their respects to the Virgin of Guadalupe, Mexico's patron saint. (Photo by Rebecca Blackwell/AP Photo)

Granada’s International Poetry Festival is an extraordinary celebration of poetry that takes place across the entire city. For a week, every February, Granada is transformed into a virtual Capital of the World’s Poetry. Photo: A girl takes part in the “Burial of arrogance and haughtiness” carnival during the IX Poetry Festival in Granada, 45 km from Managua, Nicaragua on February 20, 2013. In this occasion the festival is dedicated to Nicaraguan poet Ernesto Cardenal. (Photo by Hector Retamal/AFP Photo)

A three-year-old girl smokes a cigar during the Saint Simon celebrations in San Andres Itzapa, Guatemala, on October 28, 2019. Thousands believe that the saint helps people find work, solves family problems and cures illnesses. (Photo by Orlando Estrada/AFP Photo)