In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

In this April 28, 2015 file photo, heads of tuna on a cart are carried by a fish dealer after the day's auction at Tsukiji Wholesale Market in Tokyo. In one of the biggest of Japan's many New Year holiday rituals, early on Tuesday, January 5, 2016, Tokyo's Tsukiji market will auction off with much fanfare a huge, glistening tuna, likely destined for one of the big sushi chains. If all goes as planned, it will be the last such auction at 80-year-old Tsukiji. (Photo by Shuji Kajiyama/AP Photo)

Hello, madhouse! Listen to good music!! Love you! Yours truly, Avax. Music video: Co-Ed School (남녀공학 or 男女共学) – Bbiribbom Bbaeribbom (삐리뽐 빼리뽐)

HIV-positive 71-year-old Sylverio Hachiploa (R) talks with caregivers Glandwel Muleya (L) and Sister Abigail Mwaka Mazuba (C) in his thatched hut during a visit by a home-based care team in the village of Nedwmba, south of the Chikuni Mission in the south of Zambia February 23, 2015. The caregivers in the Jesuit-run home-based care project at the Chikuni Mission run a capacity-building and empowerment project at the household level, offering training and assistance in crop-growing and animal rearing, as well as offering companionship, pastoral care and monitoring of the antiretroviral treatment compliance of HIV-AIDS patients. (Photo by Darrin Zammit Lupi/Reuters)

Buddhists monks and children look out from the rooftop at a Buddhist mission hostel and school for underprivileged children as an international passenger flight takes off at the Netaji Subhash Chandra Bose International Airport as the authorities eased restrictions imposed as a preventive measure against the spread of the COVID-19 coronavirus, in Kolkata on July 5, 2020. (Photo by Dibyangshu Sarkar/AFP Photo)

A 180 degrees rotated photograph shows the shadows of Polina (L), a six-year-old Belarusian first grade school girl, and her father, cast on the street while on their way to Polina's first day of school, which marks the traditional start of the academic year, in Minsk, Belarus, 02 September 2019. The start of a new academic year in Belarus, officially called Day of Knowledge, is a festive day for all school and university students in the country. (Photo by Tatyana Zenkovich/EPA/EFE)

Mr. Zhong Hua, of Johns Hopkins University School of Medicine, took this image of the peripheral nerves (those outside of the brain) in an 11.5-day-old mouse embryo, magnified five times. (Photo by Zhong Hua)