“Lombard Street is an east-west street in San Francisco, California. Lombard Street is best known for the one-way section on Russian Hill between Hyde and Leavenworth Streets, in which the roadway has eight sharp turns (or switchbacks) that have earned the street the distinction of being the crookedest street in the world”. – Wikipedia

Photo: A single car drives down a typically crowded Lombard Street, San Francisco's crooked street, April 29, 2003 in San Francisco. (Photo by Justin Sullivan/Getty Images)

“Cockayne syndrome (also called Weber-Cockayne syndrome, or Neill-Dingwall Syndrome) is a rare autosomal recessive congenital disorder characterized by growth failure, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), and premature aging. Hearing loss and eye abnormalities (pigmentary retinopathy) are other common features, but problems with any or all of the internal organs are possible. It is associated with a group of disorders called leukodystrophies. The underlying disorder is a defect in a DNA repair mechanism. It is named after English physician Edward Alfred Cockayne (1880–1956)”. – Wikipedia

Photo: Mother of 12-year-old Chinese girl Sun Yangyang suffering from Cockayne syndrome, tends her at the First Affiliated Hospital of Jilin University on November 11, 2006 in Changchun of Jilin Province, China. The disease results in the senile appearance of Yangyang and also causes eyesight, hearing weakness and other problems. Doctors failed to cure the girl... (Photo by China Photos/Getty Images)

“Annelies Marie “Anne” Frank (12 June 1929 – early March 1945) was one of the most renowned and most discussed Jewish victims of the Holocaust. Acknowledged for the quality of her writing, her diary has become one of the world's most widely read books, and has been the basis for several plays and films”. – Wikipedia

Photo: Childrens watch the wax figure of Anne Frank and their hideout reconstruction at Madame Tussauds on March 9, 2012 in Berlin, Germany. (Photo by Andreas Rentz/Getty Images)

Vendor Yegor Dyachkovsky, 45, poses for a picture at an open-air market on a frosty day in Yakutsk, Russia, January 15, 2023. Yakutsk, one of the Russia's north-most cities, is hit by an extreme cold snap as the air temperature on Sunday (January 15) plunged as low as minus 51 degrees Celsius (minus 59.8 degrees Fahrenheit). (Photo by Roman Kutukov/Reuters)

School girls hold hands while looking out at the Indian Ocean at Galle Face beach in Colombo on December 9, 2022. (Photo by Ishara S. Kodikara/AFP Photo)

Drone view of vehicles after part of the ceiling collapsed in a mall in Osasco, Brazil on March 9, 2023. (Photo by Carla Carniel/Reuters)

A fuzzy caterpillar on a basil plant in west Bengal, India on December 25, 2023. The caterpillar’s defence system is its hair, which has microscopic barbs that break off easily in the skin of would-be predators. (Photo by Soumyabrata Roy/NurPhoto/Rex Features/Shutterstock)

A car drives between trees in a small park in Frankfurt, Germany, Monday, April 8, 2024. (Photo by Michael Probst/AP Photo)