In the spring of 1965, within weeks of 3,500 American Marines arriving in Vietnam, a 39-year-old Briton named Larry Burrows began work on a feature for LIFE magazine, chronicling the day-to-day experience of U.S. troops on the ground – and in the air – in the midst of the rapidly widening war. The photographs in this gallery focus on a calamitous March 31, 1965, helicopter mission; Burrows’ “report from Da Nang”, featuring his pictures and his personal account of the harrowing operation, was published two weeks later as a now-famous cover story in the April 16, 1965, issue of LIFE.

Photo: Man your battle stations: The crew chief of helicopter Yankee Papa 13, lance corporal James C. Farley, mans an M-60 machine gun during a mission near Da Nang, Vietnam on March 31, 1965. (Photo by Larry Burrows/Time & Life Pictures)

Firefighters attempt to put out a fire at an abandoned building with the protection of St. Louis City Police in St. Louis, Missouri August 19, 2015. Police fatally shot a black man they say pointed a gun at them, drawing angry crowds and recalling the racial tensions sparked by the killing of an unarmed African-American teen in nearby Ferguson, Missouri, just over a year ago. (Photo by Lawrence Bryant/Reuters)

Comandos de Salvamento rescuers Maria Martinez (L) and Ana Chichilla attend to a wounded homeless man in San Salvador, El Salvador July 16, 2016. The man was attacked with a machete by suspected gang members. In 2015, El Salvador registered a record 103 homicides per 100,000 habitants, making it one of the most dangerous countries in the world outside a war zone. But for many young people who have few chances to distance themselves from rivalries between so-called maras in their schools and neighbourhoods, a civil-society organisation called the Comandos de Salvamento, or Rescue Corps, has been a refuge. (Photo by Jose Cabezas/Reuters)

A man covered with thermal blanket walks along railway tracks beside an improvised refugee camp on the border line between Macedonia and Serbia near the northern Macedonian village of Tabanovce, Thursday, March 10, 2016. Around 1.500 migrants and refugees are stranded at Tabanovce transit center for refugees in northern Macedonia. (Photo by Boris Grdanoski/AP Photo)

Conservation staff members move the eight-years-old White Rhino Seha into a truck in Johannesburg, South Africa, 28 July 2017. Seha is the only survivor after five rhinos where poached on the same game farm. South Africa has the world's largest population of Rhinos in the world. (Photo by Kim Ludbrook/EPA/EFE)

A Cambodian man rides his motor-cart loaded with goods along a street on the outskirts Phnom Penh, Cambodia on October 30, 2017. (Photo by Tang Chhin Sothy/AFP Photo)

North Korean soldiers march during a military parade marking the 105th birth anniversary of the country's founding father Kim Il Sung in Pyongyang, North Korea, April 15, 2017. (Photo by Damir Sagolj/Reuters)

A man dressed as a demon poses for a picture as he participates in a ceremony known as Los Talciguines, as part of religious activities to mark the start of the Holy Week in Texistepeque, El Salvador, March 26, 2018. (Photo by Jose Cabezas/Reuters)